Marmosets, a kind of small non?human primates, are very suitable for research by gene modification because of their lower feeding cost and higher efficiency,shorter time of sexual maturation than macaques. Any model established by gene modification cannot be produced without assisted reproduction technology (ART) consisting of semen collection, superovulation, oocyte retrieval, in vitro maturation, in vitro fertilization, and embryo transplantation. At present, the research of these techniques is relatively comprehensive, but there are still details that need improvement. Recently, studies of gene?modified marmosets based on ART have gradually become a research focus with the development of gene editing technology. In 2009, the first report of transgenic marmosets was published by Japanese scientists, whereas related reports have not been published by Chinese scientists. This article reviews the recent progress of marmoset ART and their gene?modified models.