The good quality of laboratory animals is the foundation of laboratory animal science as a support for lifescience research. The monitoring of animal quality relies on well-established and scientific examination standards.Corynebacterium bovis is an important pathogen causing infection in nude mice, but no relevant examination standards haveyet been developed for it. The development of such standards can provide and normalize the method for detecting C. bovis,which is helpful for timely monitoring and control of this bacterium.