新型冠状病毒( SARS-CoV-2)在三文鱼食材中的活性
作者:
  • 吕 琦

    吕 琦

    中国医学科学院医学实验动物研究所,北京协和医学院比较医学中心,国家卫生健康委员会人类疾病比较医学重点实验室,新发再发传染病动物模型研究北京市重点实验室,北京市人类重大疾病实验动物模型工程技术研究中心,国家中医药管理局人类疾病动物模型三级实验室,北京 100021
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  • 刘明娅

    刘明娅

    中国医学科学院医学实验动物研究所,北京协和医学院比较医学中心,国家卫生健康委员会人类疾病比较医学重点实验室,新发再发传染病动物模型研究北京市重点实验室,北京市人类重大疾病实验动物模型工程技术研究中心,国家中医药管理局人类疾病动物模型三级实验室,北京 100021
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  • 戚菲菲

    戚菲菲

    中国医学科学院医学实验动物研究所,北京协和医学院比较医学中心,国家卫生健康委员会人类疾病比较医学重点实验室,新发再发传染病动物模型研究北京市重点实验室,北京市人类重大疾病实验动物模型工程技术研究中心,国家中医药管理局人类疾病动物模型三级实验室,北京 100021
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  • 龚姝然

    龚姝然

    中国医学科学院医学实验动物研究所,北京协和医学院比较医学中心,国家卫生健康委员会人类疾病比较医学重点实验室,新发再发传染病动物模型研究北京市重点实验室,北京市人类重大疾病实验动物模型工程技术研究中心,国家中医药管理局人类疾病动物模型三级实验室,北京 100021
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  • 周沙沙

    周沙沙

    中国医学科学院医学实验动物研究所,北京协和医学院比较医学中心,国家卫生健康委员会人类疾病比较医学重点实验室,新发再发传染病动物模型研究北京市重点实验室,北京市人类重大疾病实验动物模型工程技术研究中心,国家中医药管理局人类疾病动物模型三级实验室,北京 100021
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  • 鲍琳琳

    鲍琳琳

    中国医学科学院医学实验动物研究所,北京协和医学院比较医学中心,国家卫生健康委员会人类疾病比较医学重点实验室,新发再发传染病动物模型研究北京市重点实验室,北京市人类重大疾病实验动物模型工程技术研究中心,国家中医药管理局人类疾病动物模型三级实验室,北京 100021
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作者单位:

中国医学科学院医学实验动物研究所,北京协和医学院比较医学中心,国家卫生健康委员会人类疾病比较医学重点实验室,新发再发传染病动物模型研究北京市重点实验室,北京市人类重大疾病实验动物模型工程技术研究中心,国家中医药管理局人类疾病动物模型三级实验室,北京 100021

中图分类号:

R-33


Persistence of SARS-CoV-2 on the surface of salmon
Author:
  • LYU Qi

    LYU Qi

    Institute of Laboratory Animal Sciences, Chinese Academy of Medical Sciences (CAMS)& Comparative Medicine Center, Peking Union Medical Collage (PUMC);NHC Key Laboratory of Human Disease Comparative Medicine; Beijing Key Laboratory for Animal Models of Emerging and Reemerging Infectious; Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases; Key Laboratory of Human Diseases Animal Model, State Administration of Traditional Chinese Medicine, 100021 Beijing, China
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  • LIU Mingya

    LIU Mingya

    Institute of Laboratory Animal Sciences, Chinese Academy of Medical Sciences (CAMS)& Comparative Medicine Center, Peking Union Medical Collage (PUMC);NHC Key Laboratory of Human Disease Comparative Medicine; Beijing Key Laboratory for Animal Models of Emerging and Reemerging Infectious; Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases; Key Laboratory of Human Diseases Animal Model, State Administration of Traditional Chinese Medicine, 100021 Beijing, China
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  • QI Feifei

    QI Feifei

    Institute of Laboratory Animal Sciences, Chinese Academy of Medical Sciences (CAMS)& Comparative Medicine Center, Peking Union Medical Collage (PUMC);NHC Key Laboratory of Human Disease Comparative Medicine; Beijing Key Laboratory for Animal Models of Emerging and Reemerging Infectious; Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases; Key Laboratory of Human Diseases Animal Model, State Administration of Traditional Chinese Medicine, 100021 Beijing, China
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  • GONG Shuran

    GONG Shuran

    Institute of Laboratory Animal Sciences, Chinese Academy of Medical Sciences (CAMS)& Comparative Medicine Center, Peking Union Medical Collage (PUMC);NHC Key Laboratory of Human Disease Comparative Medicine; Beijing Key Laboratory for Animal Models of Emerging and Reemerging Infectious; Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases; Key Laboratory of Human Diseases Animal Model, State Administration of Traditional Chinese Medicine, 100021 Beijing, China
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  • ZHOU Shasha

    ZHOU Shasha

    Institute of Laboratory Animal Sciences, Chinese Academy of Medical Sciences (CAMS)& Comparative Medicine Center, Peking Union Medical Collage (PUMC);NHC Key Laboratory of Human Disease Comparative Medicine; Beijing Key Laboratory for Animal Models of Emerging and Reemerging Infectious; Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases; Key Laboratory of Human Diseases Animal Model, State Administration of Traditional Chinese Medicine, 100021 Beijing, China
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  • BAO Linlin

    BAO Linlin

    Institute of Laboratory Animal Sciences, Chinese Academy of Medical Sciences (CAMS)& Comparative Medicine Center, Peking Union Medical Collage (PUMC);NHC Key Laboratory of Human Disease Comparative Medicine; Beijing Key Laboratory for Animal Models of Emerging and Reemerging Infectious; Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases; Key Laboratory of Human Diseases Animal Model, State Administration of Traditional Chinese Medicine, 100021 Beijing, China
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Affiliation:

Institute of Laboratory Animal Sciences, Chinese Academy of Medical Sciences (CAMS)& Comparative Medicine Center, Peking Union Medical Collage (PUMC);NHC Key Laboratory of Human Disease Comparative Medicine; Beijing Key Laboratory for Animal Models of Emerging and Reemerging Infectious; Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases; Key Laboratory of Human Diseases Animal Model, State Administration of Traditional Chinese Medicine, 100021 Beijing, China

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    摘要:

    目的 研究 SARS-CoV-2 粘附在三文鱼肉上的活性保持情况,为科学防控冠状病毒提供理论依据。 方法 检测在 4℃和 22℃条件下,粘附在三文鱼肉上和 4% NaCl 仿海盐水中 SARS-CoV-2 病毒的活性情况。 结果 4℃条件下,三文鱼表面病毒活性可保持 4 d,4% NaCl 仿海盐水中病毒活性可保持 7 d,1 d 内病毒活性均衰减超过 50%。 22℃条件下,三文鱼表面病毒活性可维持 1 d,4% NaCl 仿盐水中病毒活性可维持 2 d,1 d 内病毒活性衰减均超过 50%。 结论 4℃ ~ 22℃条件下,三文鱼表面 SARS-CoV-2 病毒可存活 1~ 4 d,4%仿海盐水中 SARS-CoV-2 病毒可存活 2~ 7 d。

    Abstract:

    To investigate the persistence of SARS-CoV-2 on the surface of salmonto provide data for the control of COVID-19. Methods A 100 μL droplet of virus culture was pipetted ontothe surface of salmon and then incubated at 4℃ or 22℃ for up to 5 days. A 100 μL droplet of virus culture was also pipetted into 4% NaCl imitation seawater and then incubated at 4℃ and 22℃ for up to 9 days.The infectivity of virus collectedfrom salmon surfacesand from the 4% NaCl brine was titrated using the Vero E6 cell line. Results The virus on salmon surfacesretained viability for 4days at 4℃ , and for 1 day at 22℃ ; 50% of infectivity was lost after 1 day at both temperatures.Virus in 4% NaCl imitation seawaterretained viability for 7 days at 4℃ and for 2 days at 22℃ ; 50% of infectivity was lost after 1 day at both temperatures. Conclusions SARS-CoV-2 remained viable on salmon surfaces for 1-4 days at 4℃ and 22℃ . SARS-CoV-2 remained viable in 4% NaCl imitation sea water for 2-7 day sat 4℃ and 22℃.

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吕 琦,刘明娅,戚菲菲,龚姝然,周沙沙,鲍琳琳.新型冠状病毒( SARS-CoV-2)在三文鱼食材中的活性[J].中国比较医学杂志,2021,31(2):98~101.

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  • 收稿日期:2020-09-08
  • 在线发布日期: 2021-04-07
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