Objective Research on the modeling points of constipation animal models to provide reference for improving the success rate of modeling. Methods Using “ secret” and “ animal models” as the subject terms, all experimental journal articles from January 2015 to July 2020 in the databases of China National Knowledge Infrastructure (CNKI), Wanfang, and Weipu were searched. Summarize the types of experimental animals, modeling methods, modeling methods, modeling time, testing indicators, etc., and conduct a summary analysis. Results One hundred forty-two journal articles that met the criteria were included. Sprague Dawley ( SD) rats and Kunming ( KM) mice were mainly used to replicate animal models of constipation. Compound diphenoxylate and loperamide were the most common method of modeling. The modeling time was mostly 7 d and 14 d, and the longest was slow transit constipation of 120 d. The index detection focused on the carbon ink advancement rate, defecation function, colon tissue immunohistochemistry, and serum biochemical indicators. Conclusions Existing animal models often use drug-induced single-factor modeling and lack a multi-factor modeling evaluation system. For example, the water-restricted food control method and the low-fiber diet method are more in line with the real pathogenic factors of constipation, but there are currently few related studies. At present, research on constipation models tends to evaluate test drugs by intestinal defecation function, colonic histopathological structure, and serum biochemical indicators. With the advancement of constipation research, brain-gut axis interactions provide new ideas for constipation research, and related experimental research can be explored in future constipation experiments.