Taiyin Tiaowei-Tang is recorded in Dongeui suse bowon, which states that Taiyin Tiaowei-Tang was widely used by Taiyin people for jaundice, typhoid fever, headache, body pain, and an absence of sweating. In recent years, the pharmacological effects of Taiyin Tiaowei-Tang have been systematically studied, including its therapeutic effects on heart cerebrovascular disease, fatty liver, obesity, gastritis, and cancer. Not only does Taiyin Tiaowei-Tang have few side effects, good efficacity, and high safety but also certain therapeutic effects on diseases in multi-prescription and multitargeting strategies, and Taiyin Tiaowei-Tang is closely related to, inter alia, local climate and human geography. Taiyin Tiaowei-Tang is a popular resource used in Chinese medicine research in China. By compiling evidence from Chinese Korean medicine research and modern medicine theory, this paper reviews the pharmacological actions of Taiyin Tiaowei-Tang on various types of diseases, compares the modern pharmacological actions of its components, and summarizes the underlaying mechanisms to provide a reference for clinical and scientific research.