中药纳米技术靶向治疗脑部疾病研究进展
作者:
作者单位:

1.甘肃中医药大学药学院, 兰州 730000;2.中国人民解放军联勤保障部队第九四〇医院临床药学科, 兰州 730050;3.甘肃省高原药学行业技术中心, 兰州 730050;4.兰州大学药学院, 兰州 730000;5.西北民族大学化工学院, 兰州 730030;6.军事科学院军事医学研究院辐射医学研究所,北京 100850

中图分类号:

R-33


Research progress of targeted treatment of brain diseases with Chinese medicine nanotechnology
Author:
  • FAN Ronghui 1,6,4,5,2,3

    FAN Ronghui

    1. College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China. 2. Department of Clinical Pharmacy, the 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation Army, Lanzhou 730050. 3. Gansu Plateau Pharmaceutical Technology Center, Lanzhou 730050.
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  • YANG Zhiqiang 1,6,4,5,2,3

    YANG Zhiqiang

    2. Department of Clinical Pharmacy, the 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation Army, Lanzhou 730050. 3. Gansu Plateau Pharmaceutical Technology Center, Lanzhou 730050. 5. Institute of Chemical Technology, Northwest Minzu University, Lanzhou 730030.
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  • LI Boshen 1,6,4,5,2,3

    LI Boshen

    1. College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China. 2. Department of Clinical Pharmacy, the 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation Army, Lanzhou 730050. 3. Gansu Plateau Pharmaceutical Technology Center, Lanzhou 730050.
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  • ZHANG Yuxuan 1,6,4,5,2,3

    ZHANG Yuxuan

    1. College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China. 2. Department of Clinical Pharmacy, the 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation Army, Lanzhou 730050. 3. Gansu Plateau Pharmaceutical Technology Center, Lanzhou 730050.
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  • LI Xiaolin 1,6,4,5,2,3

    LI Xiaolin

    1. College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China. 2. Department of Clinical Pharmacy, the 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation Army, Lanzhou 730050. 3. Gansu Plateau Pharmaceutical Technology Center, Lanzhou 730050.
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  • LI Maoxing

    LI Maoxing

    1. College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China. 2. Department of Clinical Pharmacy, the 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation Army, Lanzhou 730050. 3. Gansu Plateau Pharmaceutical Technology Center, Lanzhou 730050. 4. College of Pharmacy, Lanzhou University, Lanzhou 730000. 5. Institute of Chemical Technology, Northwest Minzu University, Lanzhou 730030. 6. Institute of Radiation Medicine Sciences, Academy of Military Medical, Academy of Military Sciences, Beijing 100850
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Affiliation:

1. College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China. 2. Department of Clinical Pharmacy, the 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation Army, Lanzhou 730050. 3. Gansu Plateau Pharmaceutical Technology Center, Lanzhou 730050. 4. College of Pharmacy, Lanzhou University, Lanzhou 730000. 5. Institute of Chemical Technology, Northwest Minzu University, Lanzhou 730030. 6. Institute of Radiation Medicine Sciences, Academy of Military Medical, Academy of Military Sciences, Beijing 100850

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    摘要:

    脑部疾病在临床上较为常见,危害着人类的生命健康。血脑屏障的存在能够防止血液中的有害物质进入大脑,维持大脑的稳态环境,但同时也阻止药物进入大脑发挥药效。纳米技术具有组织靶向的优点,中药活性物质治疗脑部疾病具有良好的效果,纳米技术与中药活性物质结合治疗脑部疾病可增强靶向性。

    Abstract:

    Brain diseases are common in clinical practice. The blood-brain barrier prevents harmful substances from entering the brain and maintains homeostasis, but it also prevents drugs from entering the brain to exert effects. Nanotechnology has the advantage of tissue targeting. Active substances in Chinese traditional medicine have a good treatment effect on brain diseases. The combination of nanotechnology and active substances in Chinese traditional medicine for the treatment of brain diseases enhances targeting.

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引用本文

范容晖,阳志强,李勃深,张宇轩,李晓琳,李茂星.中药纳米技术靶向治疗脑部疾病研究进展[J].中国比较医学杂志,2023,33(6):128~140.

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  • 收稿日期:2022-11-15
  • 在线发布日期: 2023-08-18
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