In view of the problems in ethical review of domestic experimental animals for scientific research and the lack of ethical review of experimental animals for teaching, we investigated the relevant literature at home and abroad as well as the administrative regulations, national standards, industrial standards, local standards, and group standards related to the welfare and ethical review of experimental animals. This article explores the developmental process of ethical review of experimental animal welfare in China in the last 30 years, analyzes and summarizes many problems in the practical work of ethical review and the supervision and management of experimental animal welfare for scientific research, and summarizes the aspects that should be involved in ethical review education of experimental animal welfare in scientific research and teaching activities. The aim is to provide a reference to establish ethical review of experimental animal welfare for teaching in China and the content arrangement of experimental animal welfare courses in medical colleges and provide a reference for efficient ethical review of scientific research projects and articles related to animal experiments.