Abstract:Ferroptosis is a newly discovered mode of programmed cell death characterized by the accumulation of intracellular iron-dependent lipid peroxidation. Current research has mainly focused on the role of ferroptosis in the field of cancer, but increasing evidence shows that ferroptosis is also related to the occurrence of infectious diseases. Ferroptosis has accordingly been detected in cases of COVID-19, tuberculosis, and cryptococcal meningitis, as well as other diseases.This article reviews the role of ferroptosis in infectious diseases, to provide new ideas for the prevention and treatment of ferroptosis-related infectious disease