Parkinson's disease (PD) is a neurodegenerative disease characterized by the degenerative death of dopaminergic neurons in the substantia nigra, exhibiting a range of motor and non-motor symptoms that have a serious impact on the quality of life of patients. Circular RNA (circRNA, CircRNA) is a covalent closed-loop noncoding RNA that plays an important role in the progression of PD disease. This article reviews the involvement of circRNA in oxidative stress, regulation of transcriptional levels, neuroinflammation, autophagy, and α-synuclein.