The animal laboratory of pharmaceutical and biological product inspection and testing institutions undertakes important basic support tasks for testing and scientific research work. This article summarizes the management experience accumulated in the operation of our institution's CNAS-CL06 quality management system, providing reference for similar institutions in operation to ensure the scientific nature of animal experimental data. In order to ensure the scientific nature of animal experimental data, the experimental animal institution has successfully passed the CNAS accreditation of the experimental animal institution, and has completed rectification on time during on-site supervision and evaluation. At the same time, regular self inspections of the system have been carried out in accordance with the "Quality and Capability Accreditation Guidelines for Experimental Animal Breeding and Use Institutions" (CNAS-CL06). During the self inspection process, we examined issues while improving the content of the system. Starting from animal procurement, occupational health and safety, animal disease treatment and care, and facility operation emergency drills, we enriched the content of the quality management system, ensured the continuous and effective operation of the system, and ensured the effectiveness and standardization of animal experiment data. At the same time, we contributed to the management ideas of our institution in sharing animal experiment platforms, Provide hardware and software support for the construction of cloud platforms for animal experiments. This article aims to explore and form a quality management model for the experimental animal industry based on practical work, Being focused in the standardization strategy， continue to deepen the reform of standardization work, and give full play to the basic and strategic role of standardization in the modernization of the animal experiments system.