Ferroptosis is a newly discovered mode of programmed cell death characterized by the accumulation of intracellular iron-dependent lipid peroxidation. At present, the research on ferroptosis mainly focuses on the field of cancer, but more and more evidence shows that ferroptosis is related to the occurrence of infectious diseases, and ferroptosis has been found in Corona Virus Disease 2019, tuberculosis and cryptococcal meningitis and other diseases. This article reviews the role of ferroptosis in infectious diseases, in order to provide new ideas for the prevention and treatment of ferroptosis related infectious diseases.