Endometriosis (EMs)? is a common challenge in global women"s health. In recent years, ferroptosis, as an emerging form of regulated cell death, has attracted attention in EMs research. In terms of disease mechanisms, ferroptosis drives ovarian EMs fibrosis through iron overload induction, and promotes disease progression by regulating multiple signaling pathways such as p38MAPK/STAT6, enhancing angiogenesis, autophagy, etc. In terms of infertility, ferroptosis affects embryo development and ovarian function, significantly reducing fertility. In terms of diagnosis, the high expression of ferroptosis-related genes provides potential biomarkers for early diagnosis of EMs, effectively distinguishing patients from healthy individuals, and has important clinical application value. In terms of treatment strategies, non-natural compounds like Erastin, as well as natural compounds like resveratrol, ursolic acid, baicalein, etc., show potential therapeutic effects, relieving the pathological process and related symptoms of EMs. Therefore, this article