药物成瘾生物标志物的研究进展
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作者单位:

国家卫健委毒品依赖和戒治重点实验室,昆明医科大学法医学院

基金项目:

云南省重点研发计划项目(202303AC100021);云南省教育厅科学研究(2024J0156)


Research Progress on The Biomarkers of Drug Addiction
Author:
Affiliation:

Key Laboratory of Drug Dependence and Treatment,National Health Commission,School of Forensic Medicine,Kunming Medical University

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    摘要:

    药物成瘾是一种慢性疾病,不仅会造成个人生理和心理的损害,更重要的是还会对社会造成严重危害。生物标志物是指在健康人群和患者之间存在明显差异的指标,对疾病的诊断和治疗具有重要意义。近年来,药物成瘾患者越来越多,新型毒品的种类和数量也在不断增加,因此对药物成瘾生物标志物的研究受到广泛关注。在多种生物检材中都存在潜在的生物标志物,为此本文综述了毛发、血液、尿液、粪便中可能的生物标志物,为进一步探索药物成瘾的生物特征性标志物提供参考,同时为药物成瘾的临床诊断及治疗提供科学基础。

    Abstract:

    Drug addiction is a chronic disease that not only causes serious physical and psychological harm to the individual, but more importantly, it also causes serious damage to society. Biomarkers are indicators that differ significantly between healthy people and patients, and are important for both diagnosis and treatment of diseases. Due to the increasing number of drug-addicted patients in recent years and the increasing variety and number of new drugs, the study of biomarkers of drug addiction has been increasing, and biomarkers are present in different biological samples. This paper reviews the biomarkers in hair, blood, urine and faeces, which can help to explore the biosignature markers of drug addiction and facilitate the clinical diagnosis and treatment of drug addiction.

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  • 收稿日期:2024-09-18
  • 最后修改日期:2024-12-08
  • 录用日期:2025-02-18
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