Non-human primate (NHP) experimental animals are key strategic resources for biomedical research, and their management needs to balance scientific validity and regulatory compliance. To address limitations of conventional management systems—such as fragmented information, operational inefficiencies, and insufficient traceability—this study leverages the neuroscience research framework of the Shanghai Center for Brain Science and Brain-Inspired Technology in animal management experience and brain science research tasks to develop an integrated information management system for NHP experimental animals. The system consolidates functional modules encompassing individual profiles, health monitoring, quarantine records, breeding pedigrees, medical interventions, permitting documentation, technical services, personnel training, and resource sharing. Through digitized management, it enables real-time data updates, dynamic early-warning mechanisms, and multidimensional analytics, while embedding institutional ethical review processes and regulatory compliance protocols. Implementation practices demonstrate that the system significantly enhances operational efficiency in animal management and elevates collaborative research capabilities, offering a reference paradigm for analogous platforms.