Abstract:Objective To compare the effect of berberine and additive on serum glucose and lipid level.MethodsType 2 diabetic model was induced by both high lipid food and low dose of streptozotocin(STZ) in mice.The number of 100 three month's mice were randomly divided into normal group,type 2 diabetic model group,berberine treated group,berberine and low dose additive treated group,berberine and high dose additive treated group and metformin treated group.Every group were administered through intragastric administrat...