Objective To generate the CTF1 gene transgenic mice specifically expressed in nervous tissues and to make an animal model for the study of its function and effects on Alzheimer's disease.Methods Transgenic mice were created by the methods of microinjection.The genotype of transgenic lines was identified by PCR.The brain specific expression of the CTF1 gene was analyzed by Western Blot.The histological changes of the brain from the transgenic mice were analyzed by microscope observation.Results Two transgeni...