Objective To investigate the epizoic parasites infection in tree shrew( tupaia belangeri chinensis) ，and to provide a basis for seting up the quality standard of tree shrew． Methods Sixty wild tree shrews were executed by dislocation，and took hair to production from oxter、ear、groin、round anus of wild tree shrews and F1 generation tree shrews， then detected the epizoic parasites under platoscope and microscope． Results The natural infectious rate of the epizoic parasites in wild tree shrew and F1 generation tree shrews were respectively louse ( 25% /6% )、flea ( 5% /0 )、cicadas (1. 6% /0)、bloodsucker(1. 6% /0)、infection with louse and flea(1. 6% /0) ． Conclusions The most of epizoic parasites identified in tree shrews were louse and fleas，secondly were cicadas and bloodsucker． As a whole，infectious rate of the wild tree shrews was obvious more than F1 generation tree shrews，and we gained good effect by taking a preventing and treating measures．