Comparison of Different Angiographic Imaging Techniques for Evaluation of Elastase-Induced Saccular Aneurysm in Rabbit
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1. Outpatient Department,Military Unit 96351 of PLA,Lanzhou 730100,China;2. Second Department of Surgery,536 Hospital of PLA,Xi’ning 810007

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    Abstract:

    Objective To evaluate the feasibility of conventional intra-arterial angiography, intra-venous angiography,transventricular angiography and angiography through the central artery of the left ear in assessment the of elatase-induced saccular aneurysm in rabbits. Methods Ten New Zealand white rabbits underwent surgical operation to develop a model of elastase-induced saccular aneurysms at the origin of the right common carotid artery. Each rabbit underwent conventional intra-arterial digital subtraction angiography, intra-venous digital substraction angiography,transventricular angiography and angiography through the central artery of the left ear at 3 weeks after the modeling procedure. Using an external sizing reference,the diameter of aneurysm,including the width,height and neck,measured.The data obtained by different angiographic imaging were compared by one-way repeated measures ANOVA. Results The aneurysm morphology in the tested animals was clearly displayed by conventional intra-arterial angiography,intra-venous digital substraction angiography,transventricular angiography and angiography through the central artery of the left ear in rabbits,respectively. There were no significant differences in the width,height and neck of aneurysms measured by different angiographic methods ( P = 0. 646,0. 427 and 0. 625,respectively) . Conclusions The different angiographies can clearly show the size of elastase-induced saccular aneurysms in rabbits,and an appropriate angiographic method can b selected according to different experimental aims and conditons.

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History
  • Received:March 06,2011
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  • Online: December 05,2025
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