ObjectiveTo establish the normal range of body weight and blood biochemical indexes of Tianjin wild (TW) inbred mice, and to determine their coat color gene. MethodsThe body weight and blood biochemical parameters of TW inbred mice were examined. The coat color gene was determined by mating with DBA/2 mice. ResultsWhen the TW mice were younger than six weeks old, there was no significant difference between the body weights of TW male and female mice (P<0.05). When the TW mice were older than six weeks of age, the body weight of TW male mice was higher than that of TW female mice (P<0.05). Compared with the female group, the total protein was higher in male group (P<0.05), while the triglycerides were lower (P<0.05). The coat color gene analysis revealed that hair color of first generation hybrid was white belly wild color, and its gene type was AWAWBBccDD. ConclusionsTW inbred mice have their own characteristic blood biochemical indexes, and some are different from those of commonly used inbred mouse strains. The coat color gene of TW mice is homozygosis. 