Due to the reduced cerebral blood supply, chronic cerebral circulation insufficiency (CCCI) causes diverse pathological damages to different degrees in the brain, and consequently leading to memory deterioration and a series of symptoms. Researches on pathological mechanism and repairing of CCCI damages are one of hot spots in neuroscience. In this article, current researches on animal models of chronic cerebral ischemia are reviewed. The authors would summarize the model preparation, evaluation of methodology and frequent questions, and to provide useful reference for further studies on chronic cerebral circulation insufficiency.