Objective To explore the differences of the membrane pressure about goat paranasal sinus membrane, and analyze the reasons that may cause these. The discussion can provide the theoretical basis and guidance for the issues of the maxillary sinus floor augmentation related to the membrane.Methods The membrane was cut into desired size from every sinus membrane. The pressure data could be measured byusing the push-pull gauge and the homemade fixtures. A paired t-test was used to determine the relationships between the parameters, P<0.05 were accepted as statistically significant.Results The membrane pressure of the top of maxillary sinus was 260.08±80.12 Kpa, the bottom was 306.90±94.37 Kpa, the frontal sinus membrane was 121.72±31.72 Kpa. The mean differences of membrane pressure between the top of maxillary sinus and the frontal sinus, the bottom and the frontal, the top and the bottom were statistically significant(P<0.05). The membrane pressure of the top of maxillary sinus was bigger than the frontal sinus membrane, The membrane pressure of the bottom of maxillary sinus was bigger than the frontal sinus membrane, The membrane pressure of bottom of maxillary sinus was bigger than the top.Conclusions The membrane pressure among the frontal sinus, the top of maxillary sinus, and the bottom of maxillary sinus were different, and increased in turn.