Progress in the comparison of physiological structures and functions of mammalian bipolar cells

doi:10.3969/j. issn. 1671 -7856. 2018. 07. 017

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Progress in the comparison of physiological structures and functions of mammalian bipolar cells
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                        10.3969/j. issn. 1671 -7856. 2018. 07. 017
                    
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                        ZHANG Chi1ZHANG Chi
Department of Ophthalmology, the Fourth Affiliated Hospital of Kunming Medical University; Yunnan Eye Institute, Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology, Kunming 650021, China.
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HU Min1HU Min
Department of Ophthalmology, the Fourth Affiliated Hospital of Kunming Medical University; Yunnan Eye Institute, Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology, Kunming 650021, China.
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SUN Xiaomei2SUN Xiaomei
Institute of Medical Biology, Peking Union Medical College and Chinese Academy of Medical Sciences, Kunming 650118
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ZHOU Yuan1ZHOU Yuan
Department of Ophthalmology, the Fourth Affiliated Hospital of Kunming Medical University; Yunnan Eye Institute, Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology, Kunming 650021, China.
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Affiliation:(1. Department of Ophthalmology, the Fourth Affiliated Hospital of Kunming Medical University; Yunnan Eye Institute, Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology, Kunming 650021, China. 2. Institute of Medical Biology, Peking Union Medical College and Chinese Academy of Medical Sciences, Kunming 650118)
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Abstract:

Retinal bipolar cells are intermediate neurons in the signal pathway of the mammalian visual system. They receive signal inputs from photoreceptors (cone and rod cells) and transmit information to amacrine and ganglion cells after integrating information. Recent studies have shown that, through immunocytochemical staining, biophysics, pharmacology, membrane capacitance measurement, fluorescent biosensors, and two?photon microscopy, at the point where the visual path first diverges, a more comprehensive understanding of the entire category of neurons in the range of arrival can be obtained. Here, this article reviews the research progress in comparisons of the unique physiological structures and functions of different mammalian retinal bipolar cells and synaptic remodeling by immunocytochemical methods.

Key words:mammals; bipolar cells; immunohistochemistry; plasticity

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Received:February 10,2018
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Online: August 08,2018
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