Research advances for Pig⁃a gene mutation assay

doi:10.3969/j. issn. 1671 -7856. 2018. 08. 024

Home > Archive>Volume 28, Issue 8, 2018 >135-140. DOI:10.3969/j. issn. 1671 -7856. 2018. 08. 024

Research advances for Pig⁃a gene mutation assay
DOI:
                        10.3969/j. issn. 1671 -7856. 2018. 08. 024
                    
CSTR:
                        [cstr]
                    
Author:
                        ZHENG DandanZHENG Dandan
Shenzhen Institute for Drug Control, Shenzhen Key Laboratory of Drug Quality Standard Research,Shenzhen 518057, China
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site
QIN MeirongQIN Meirong
Shenzhen Institute for Drug Control, Shenzhen Key Laboratory of Drug Quality Standard Research,Shenzhen 518057, China
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site
WANG XiaoweiWANG Xiaowei
Shenzhen Institute for Drug Control, Shenzhen Key Laboratory of Drug Quality Standard Research,Shenzhen 518057, China
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site
WANG PingWANG Ping
Shenzhen Institute for Drug Control, Shenzhen Key Laboratory of Drug Quality Standard Research,Shenzhen 518057, China
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site

                    
Affiliation:(Shenzhen Institute for Drug Control, Shenzhen Key Laboratory of Drug Quality Standard Research,Shenzhen 518057, China)
Clc Number:R-33
Fund Project:

Article

Figures

Metrics

Reference

Cited by

Materials

Comments

Abstract:

It is important to establish sensitive and reliable method for genotoxicity tests for evaluating the potential mutagenicity of chemicals. In recent years, a new in vivo genotoxicity test based on Pig?a gene mutation has been developed and recognized to be useful for regulatory safety assessment because of its potential for clinical translation, its remarkable sensitivity to mutagenic agents, its relatively low cost, and its potential for integration with other in vivo tests as well as for reducing animal use. This paper mainly reviews the application and development of the Pig?a gene mutation assay.

Key words:ZHENG Dandan, QIN Meirong, WANG Xiaowei, WANG Ping

Get Citation

Copy

Article Metrics

Abstract:
PDF:
HTML:
Cited by:

History

Received:January 11,2018
Revised:
Adopted:
Online: September 17,2018
Published:

Home

About this journal

Editorial Board

Info for Author

Contact Us

中文版

Get Citation

Share

Article Metrics

History

Article QR Code