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Home > Archive>Volume 29, Issue 1, 2019 >107-113. DOI:10.3969/j. issn. 1671 -7856. 2019. 01. 019
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A review of experimental liver injury models in mice
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[cstr]
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(1. Guangxi University of Chinese Medicine, Nanning 530222, China.2. The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning 530023)

Clc Number:

R-33

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    Abstract:

    To select the appropriate mouse model of liver injury is of great significance for the research on prevention and treatment of liver disease, the study of its pathogenesis and the screening of drugs to protect the liver.According to references published internationally, mouse models of liver injury were classified into chemical,pharmacological, immunological, alcoholic, and partial hepatectomy studies. Based on the classification of models of liver injury in mice, the pathogenesis, dosage of drugs, time of model formation, applicable scope, and advantages and disadvantages were reviewed to provide a reference for the selection of experimental mouse liver injury models.

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History
  • Received:July 23,2018
  • Online: February 11,2019
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