Role of immune cells in diabetic macroangiopathy

doi:10.3969/j. issn. 1671 -7856. 2019. 03. 017

Home > Archive>Volume 29, Issue 3, 2019 >98-102. DOI:10.3969/j. issn. 1671 -7856. 2019. 03. 017

Role of immune cells in diabetic macroangiopathy
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                        10.3969/j. issn. 1671 -7856. 2019. 03. 017
                    
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                        YANG Chan1YANG Chan
Clinical Medical College/ Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610075, China.
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YANG Qiangfei2YANG Qiangfei
Jianyang People’s Hospital, Jianyang 641400.
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XIE Ziyan1XIE Ziyan
Clinical Medical College/ Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610075, China.
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YAN Ran1YAN Ran
Clinical Medical College/ Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610075, China.
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CAI Xueqin1CAI Xueqin
Clinical Medical College/ Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610075, China.
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XIE Chunguang3XIE Chunguang
Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075
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Affiliation:(1. Clinical Medical College/ Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610075, China. 2. Jianyang People’s Hospital, Jianyang 641400. 3. Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075)
Clc Number:R-33
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Abstract:

Diabetic macrovascular disease is a low-grade inflammatory state, and its pathological basis is sustainedvascular injury caused by immune inflammatory reaction. An imbalance of immune cells leading to immune inflammatorymicroenvironmental disorder in the large blood vessels is the central immune inflammatory reaction in this condition, but itsexact pathological mechanism is unclear. Therefore, this paper presents a review of the presence and rde macrophages,lymphocytes, dendritic cells, and mast cells, among others, in this condition. The immune cell development pathway isbriefly analyzed here with respect to the possible mechanisms of involvement of immune cells in the development of diabetic macroangiopathy.

Key words:diabetic macroangiopathy; immune cell; review; immune inflammatory response; macrovascular

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Received:August 20,2018
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Online: April 10,2019
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