Bronchiolitis obliterans (BO) is a clinical syndrome characterized by chronic obstruction of thebronchioles. Pathologically, BO is characterized by partial or complete occlusion of the bronchioles. Pathological typesinclude constrictive bronchiolitis and proliferative bronchiolitis. Ideal animal models have contributed to characterizing thepathogenesis of BO and exploring new therapeutic schedules. Animal models of BO have been established by differentmethods. These models each have their own advantages and limitations. This article reviews the recent progress in research on animals models of nontransplant BO.