Construction of animal models of inhalation lung injury: a review

doi:10.3969/j. issn. 1671 -7856. 2019. 10. 022

Home > Archive>Volume 29, Issue 10, 2019 >126-130. DOI:10.3969/j. issn. 1671 -7856. 2019. 10. 022

Construction of animal models of inhalation lung injury: a review
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                        10.3969/j. issn. 1671 -7856. 2019. 10. 022
                    
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                        WANG Dongmei1WANG Dongmei
The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin, 150040, China
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MU Yungjing2MU Yungjing
Heilongjiang University of Chinese Medicine, Harbin,150040
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ZHOU Qian2ZHOU Qian
Heilongjiang University of Chinese Medicine, Harbin,150040
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SHI Pei1SHI Pei
The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin, 150040, China
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HUO Yuting2HUO Yuting
Heilongjiang University of Chinese Medicine, Harbin,150040
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WANG Yingying2WANG Yingying
Heilongjiang University of Chinese Medicine, Harbin,150040
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Affiliation:(1. The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin, 150040, China;2. Heilongjiang University of Chinese Medicine, Harbin,150040)
Clc Number:R-33
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Abstract:

Selection of suitable animal models of haze inhalation lung injury is important for studies of the pathogenesis, prevention, and treatment of haze inhalation lung injury. Animal models of haze inhalation lung injury are classified as physical, chemical, biological, and granular lung injury. In this article, the infusion method, reagents, and dose selection were reviewed to provide references for the construction of haze inhalation lung injury animal models.

Key words:haze inhalation lung injury model; physical lung injury; chemical lung injury; biological lung injury;granular lung injury; model establishment

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Received:April 09,2019
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Online: November 07,2019
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