Methods for animal models of chronic obstructive pulmonary disease

doi:10. 3969 / j.issn.1671-7856. 2020. 03. 019

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Methods for animal models of chronic obstructive pulmonary disease
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                        10. 3969 / j.issn.1671-7856. 2020. 03. 019
                    
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                        LIU DiLIU Di
1.Beijing University of Chinese Medicine,Beijing 100029,China. 2.Department of TCM Pulmonary Diseases, China-Japan Friendship Hospital. Center of Respiratory Medicine, China-Japan Friendship Hospital. National Clinical Research Center for Respiratory Diseases,Beijing 100029
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ZHANG Hongchun2ZHANG Hongchun
Department of TCM Pulmonary Diseases, China-Japan Friendship Hospital. Center of Respiratory Medicine, China-Japan Friendship Hospital. National Clinical Research Center for Respiratory Diseases,Beijing 100029
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Affiliation:1.Beijing University of Chinese Medicine,Beijing 100029,China. 2.Department of TCM Pulmonary Diseases, China-Japan Friendship Hospital. Center of Respiratory Medicine, China-Japan Friendship Hospital. National Clinical Research Center for Respiratory Diseases,Beijing 100029
Clc Number:R-33
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Abstract:

Chronic obstructive pulmonary disease(COPD) is a kind of airway inflammatory disease, which has a high morbidity and mortality, and brings heavy burden to patients and society. And its pathogenesis and treatment methods have not been thoroughly studied at present. Although animal models can only simulate part of the characteristics of the disease, they are indispensable for further research on the physiology, pathology and treatment of COPD. This paper summarizes the animal models, modeling methods and measurement indexes of animal models of COPD in combination with the literatures relevant to COPD modeling in recent three years in PubMed

Key words:chronic obstructive pulmonary disease; emphysema; animal models; modeling methods; inflammation; cigarette smoke

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Received:November 07,2019
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Online: August 19,2020
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