Investigation on the infection of SARS-CoV-2 in laboratory animals
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1.Laboratory Animal Institute, National Institutes for Food and Drug Control, Beijing 100050, China. 2. Dongying Center for Disease Control and Prevention, Dongying 257091

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    Abstract:

    Objective We investigated the infection of SARS-CoV-2 in laboratory animals. Methods The double-antigen sandwich ELISA method was used to detect SARS-CoV-2 antibodies in the serum samples from five laboratory animal production facilities in 2020, including 90 mice of 25 strains, 38 rats of 5 strains, 20 guinea pigs, 27 rabbits of 3 strains and 5 beagle dogs. Results A total of 90 mice, 38 rats, 20 guinea pigs, 27 rabbits, and 5 beagle dogs sent for testing by various experimental animal production units in 2020 were tested for SARS-CoV-2 antibodies by double antigen sandwich ELISA, and the result were all negative. Conclusions Preliminary studies have not confirmed the existence of SARS-CoV-2 in laboratory animals.

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History
  • Received:June 28,2020
  • Online: October 26,2020
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