Establishment of common animal models of asthma

doi:10. 3969 / j.issn.1671-7856. 2020. 11. 016

Home > Archive>Volume 30, Issue 11, 2020 >97-101. DOI:10. 3969 / j.issn.1671-7856. 2020. 11. 016

Establishment of common animal models of asthma
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                        10. 3969 / j.issn.1671-7856. 2020. 11. 016
                    
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                        LI YongxingLI Yongxing
Department of Anesthesiology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China
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ZHONG MingZHONG Ming
Department of Anesthesiology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China
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WANG YongWANG Yong
Department of Anesthesiology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China
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MA WuhuaMA Wuhua
Department of Anesthesiology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China
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Affiliation:Department of Anesthesiology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China
Clc Number:R-33
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Abstract:

Asthma is a common chronic respiratory inflammatory disease. Additional asthma-related pathophysiology research and new drug trials are needed. This would be greatly expedited using corresponding animal asthma models. However, to date, there is no ideal model that can represent all the characteristics of the complex disease of human asthma. Therefore, this review provides the characteristics of commonly used animals currently used to make asthma models, different modeling method , different selected reagents, and the time required for modeling, which should help researchers in choosing appropriate animals, Methods and allergens.

Key words:asthma; animal model; modeling time

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Received:March 13,2020
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Online: December 25,2020
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