Ferroptosis is a recently discovered type of programmed cell death and accumulating evidence suggests that it plays an important role in respiratory diseases through a variety of mechanisms, such as iron-dependent lipid peroxidation and reactive oxygen species ( ROS) production; its role in the occurrence and development of respiratory diseases cannot be ignored. This review summarizes current knowledge of the role and mechanism of ferroptosis in the development and progression of respiratory diseases, and provides a theoretical basis for further research.