HE Xiaoduo
China-America Institute of Neuroscience, Xuanwu Hospital, Beijing 100053,ChinaWU Di
China-America Institute of Neuroscience, Xuanwu Hospital, Beijing 100053,ChinaWU Longfei
China-America Institute of Neuroscience, Xuanwu Hospital, Beijing 100053,ChinaCHEN Jian
Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053DING Yuchuan
China-America Institute of Neuroscience, Xuanwu Hospital, Beijing 100053,China1.China-America Institute of Neuroscience, Xuanwu Hospital, Beijing 100053,China. 2. Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053
R-33
Ischemic stroke is still a heavy burden due to its higher incidence and mortality rate. Therapeutic hypothermia is considered as the most promising treatment for ischemic stroke. However, there is still an uncertain efficacy in clinical trials despite evidence of efficacy in pre-clinical experiments. Nonhuman primates serve as the bridge between pre-clinical and clinical studies. We summarize recent progress of therapeutic hypothermia in stroke models of nonhuman primates. We want to promote the translation of therapeutic hypothermia in clinical trials.
