Parkinson’s disease (PD), the second most prevalent neurodegenerative disorder worldwide, lacks a cure. The discovery and evaluation of treatment method are dependent on nonhuman primate (NHP) models of PD. A reliable and valid animal model can contribute to understanding the pathogenesis, diagnosis, therapy, and drug discovery related to PD. Rodents and invertebrates are commonly used to establish PD models. However, Results using rodent and invertebrate models do not accurately represent the behavioral and pathological characteristics of human PD. NHPs are the closest animals to humans in terms of physiology, structure, and immunology, which makes them suitable for studies to understand the mechanisms of disease and establish new therapies. This article reviews the progression of PD models in NHPs, thereby providing a reference for PD model establishment.