PAN Xuen
Guangdong Provincial Public Laboratory of Analysis and Testing Technology, Guangdong Provincial Key Laboratory of Emergency Test for Dangerous Chemicals, Institute of Analysis, Guangdong Academy of Sciences (China National Analytical Center Guangzhou), Guangzhou 510070, ChinaLU Zhangshun
Guangdong Provincial Public Laboratory of Analysis and Testing Technology, Guangdong Provincial Key Laboratory of Emergency Test for Dangerous Chemicals, Institute of Analysis, Guangdong Academy of Sciences (China National Analytical Center Guangzhou), Guangzhou 510070, ChinaYANG Guang
Guangdong Provincial Public Laboratory of Analysis and Testing Technology, Guangdong Provincial Key Laboratory of Emergency Test for Dangerous Chemicals, Institute of Analysis, Guangdong Academy of Sciences (China National Analytical Center Guangzhou), Guangzhou 510070, ChinaZHONG An
Guangdong Provincial Public Laboratory of Analysis and Testing Technology, Guangdong Provincial Key Laboratory of Emergency Test for Dangerous Chemicals, Institute of Analysis, Guangdong Academy of Sciences (China National Analytical Center Guangzhou), Guangzhou 510070, ChinaHUANG Zhipeng
Guangdong Provincial Public Laboratory of Analysis and Testing Technology, Guangdong Provincial Key Laboratory of Emergency Test for Dangerous Chemicals, Institute of Analysis, Guangdong Academy of Sciences (China National Analytical Center Guangzhou), Guangzhou 510070, ChinaHE Zhirong
Guangdong Provincial Public Laboratory of Analysis and Testing Technology, Guangdong Provincial Key Laboratory of Emergency Test for Dangerous Chemicals, Institute of Analysis, Guangdong Academy of Sciences (China National Analytical Center Guangzhou), Guangzhou 510070, ChinaGuangdong Provincial Public Laboratory of Analysis and Testing Technology, Guangdong Provincial Key Laboratory of Emergency Test for Dangerous Chemicals, Institute of Analysis, Guangdong Academy of Sciences (China National Analytical Center Guangzhou), Guangzhou 510070, China
R-33
The development of alternative tests for skin corrosion and skin irritation were reviewed, and the Integrated Approach on Testing and Assessment (IATA), which was recently adopted by the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), was introduced. Focusing on the principles, Methods and scope of various alternative tests, the advantages and limitations of these tests in the application of IATA will be discussed to provide guidance for the classification of chemicals causing skin corrosion and irritation by effective utilization of the alternative tests and the data derived from these tests.
