The role of the toll-like receptor 4 signaling pathway in alcoholic liver injury

doi:10. 3969 / j.issn.1671-7856. 2021. 10. 019

Home > Archive>Volume 31, Issue 10, 2021 >126-130. DOI:10. 3969 / j.issn.1671-7856. 2021. 10. 019

The role of the toll-like receptor 4 signaling pathway in alcoholic liver injury
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                        10. 3969 / j.issn.1671-7856. 2021. 10. 019
                    
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Author:
                        YANG Donghan1YANG Donghan
Institute of Nutrition and Food Health, Baotou Medicine College, Baotou 014040, China
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ZHANG Wenlong2ZHANG Wenlong
the First Affiliated Hospital of Baotou Medical College, Baotou Medicine College, Baotou 014040
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HOU Ruili1HOU Ruili
Institute of Nutrition and Food Health, Baotou Medicine College, Baotou 014040, China
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LI Kexin1LI Kexin
Institute of Nutrition and Food Health, Baotou Medicine College, Baotou 014040, China
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ZHANG Hongran1ZHANG Hongran
Institute of Nutrition and Food Health, Baotou Medicine College, Baotou 014040, China
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GE Na1GE Na
Institute of Nutrition and Food Health, Baotou Medicine College, Baotou 014040, China
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Affiliation:1.Institute of Nutrition and Food Health, Baotou Medicine College, Baotou 014040, China. 2. the First Affiliated Hospital of Baotou Medical College, Baotou Medicine College, Baotou 014040
Clc Number:R-33
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Abstract:

According to data on China’s disease burden in 2019 published by the Lancet, alcohol consumption is the 10th leading risk factor for death. However, the pathogenesis of alcoholic liver injury caused by drinking is very complicated, and there is still no final conclusion. The toll-like receptor 4 signaling pathway has a key role in the occurrence and development of alcoholic liver injury. Therefore, this article reviews the role of the toll-like receptor 4 signal transduction pathway in alcoholic liver injury.

Key words:alcoholic liver injury; toll-like receptor 4 signaling pathway; endotoxin

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Received:November 04,2020
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Online: November 29,2021
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