Research progress of genetic models of common mental diseases in rats and mice

doi:10. 3969 / j.issn.1671-7856. 2021. 11. 018

Home > Archive>Volume 31, Issue 11, 2021 >119-126. DOI:10. 3969 / j.issn.1671-7856. 2021. 11. 018

Research progress of genetic models of common mental diseases in rats and mice
DOI:
                        10. 3969 / j.issn.1671-7856. 2021. 11. 018
                    
CSTR:
                        [cstr]
                    
Author:
                        LUO Zhuohui1LUO Zhuohui
Key Laboratory of Human Disease Comparative Medicine, National Health Commission of China (NHC), Institute of Laboratory Animal Science, Peking Union Medicine College, Chinese Academy of Medical Sciences, Beijing 100021, China
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site
PANG Shuo1PANG Shuo
Key Laboratory of Human Disease Comparative Medicine, National Health Commission of China (NHC), Institute of Laboratory Animal Science, Peking Union Medicine College, Chinese Academy of Medical Sciences, Beijing 100021, China
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site
ZHANG LianfengZHANG Lianfeng
1.Key Laboratory of Human Disease Comparative Medicine, National Health Commission of China (NHC), Institute of Laboratory Animal Science, Peking Union Medicine College, Chinese Academy of Medical Sciences, Beijing 100021, China. 2. Neuroscience Center, Chinese Academy of Medical Sciences, Beijing 100730
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site

                    
Affiliation:1.Key Laboratory of Human Disease Comparative Medicine, National Health Commission of China (NHC), Institute of Laboratory Animal Science, Peking Union Medicine College, Chinese Academy of Medical Sciences, Beijing 100021, China. 2. Neuroscience Center, Chinese Academy of Medical Sciences, Beijing 100730
Clc Number:R-33
Fund Project:

Article

Figures

Metrics

Reference

Cited by

Materials

Comments

Abstract:

With the changes in living conditions of modern society, patients with mental disorders represented by depression and anxiety are increasing yearly. However, the low cure rate of existing treatment measures needs to be improved. Clarifying the pathological mechanisms of these diseases is of great significance for their prevention and treatment. Such models include induced and genetic models. Genetic models have the advantages of a stable phenotype, clear pathological processes and a long treatment window. This article summarizes the genetic models of common mental disorders in rats and mice, briefly introduces the behavioral phenotypic characteristics and provides references for experimental psychiatric research based on animal behavior.

Key words:mental disorders; genetic models; animal behavior

Get Citation

Copy

Article Metrics

Abstract:
PDF:
HTML:
Cited by:

History

Received:March 01,2021
Revised:
Adopted:
Online: December 17,2021
Published:

Home

About this journal

Editorial Board

Info for Author

Contact Us

中文版

Get Citation

Share

Article Metrics

History

Article QR Code