Objective To explore establishment method of three-dimensional modeling and 3D printing of pulmonary in minipigs, and apply the constructures to clinical trials. Methods Four Bama minipigs were subjected to general anesthesia and CT angiography. Imaging data were reconstructed by MIMICS software into tissues of pulmonary and used to print the indicated structures of pulmonary vessels and bronchus using a 3D printer. Results The three- dimensional model from the CT angiography data revealed three to four levels of anatomical structure of pulmonary vessels and bronchus, lobar fissure and partial intersegmental planes. The 3D model, rotating and auto-zooming is consistent with the pulmonary tissue. Conclusions Constructures of pulmonary vessels, bronchus and whole pulmonary tissue in Bama minipigs could be reconstructed by three-dimensional reconstruction and 3D printing technology, which provide reference for comparative medical research and have been materinals for thoracic surgery training.