Research and progress of rheumatoid arthritis experimental models

doi:10. 3969 / j.issn.1671-7856. 2022. 05. 016

Home > Archive>Volume 32, Issue 5, 2022 >107-114. DOI:10. 3969 / j.issn.1671-7856. 2022. 05. 016

Research and progress of rheumatoid arthritis experimental models
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                        10. 3969 / j.issn.1671-7856. 2022. 05. 016
                    
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                        LU Dandan1LU Dandan
Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
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HAN Xiaoyan2HAN Xiaoyan
College of Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617
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ZHANG Han1ZHANG Han
Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
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LI Lin1LI Lin
Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
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FANG Shiming1FANG Shiming
Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
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Affiliation:1.Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China. 2. College of Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617
Clc Number:R-33
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Abstract:

Rheumatoid arthritis ( RA) is a common autoimmune disease characterized by chronic synovial inflammation with joint cartilage and bone damage. Under Traditional Chinese Medicine, RA is categorized as a “ Bi disease.” Various RA models have been developed, including induced model, spontaneous genetic modification model, and model of Traditional Chinese Medicine syndrome. These models were reviewed and summarized in terms of their theoretical basis, typical characteristics, evaluation method , main usages, and degree of agreement. This paper also deals with the relationship between intestinal flora and RA to provide a reference for follow-up research.

Key words:Traditional Chinese Medicine; rheumatoid arthritis; experimental model; intestinal flora

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Received:July 12,2021
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Online: July 05,2022
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