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Home > Archive>Volume 32, Issue 11, 2022 >95-100. DOI:10. 3969 / j.issn.1671-7856. 2022. 11. 012
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Research progress on the mechanism of microRNA-regulation of intestinal barrier
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1. School of Acupuncture-Moxibustion / Third Affiliated Hospital, Chengdu University of Chinese Medicine, Chengdu 610075, China.2. Graduate School, Chengdu University of Chinese Medicine, Chengdu 610075

Clc Number:

R-33

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    Abstract:

    Intestinal barrier dysfunction is an important etiological and pathological feature of many diseases. The role of microRNA in intestinal barrier injury is the subject of more and more attention and increasingly focused research. Studies have found that microRNA can be involved in the destruction or protection of intestinal barrier function by combining different targets to regulate structural proteins, apoptosis, immunity, inflammation, and oxidative stress. The research is summarized, and different mechanisms of microRNA regulation of the intestinal barrier are discussed, to explore the potential value of microRNA when studying the mechanisms, diagnosis, and treatment of these diseases.

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History
  • Received:April 18,2022
  • Online: January 18,2023
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