Astrocytes play a major role in the pathogenesis of hepatic encephalopathy

doi:10. 3969 / j.issn.1671-7856. 2023. 03. 014

Home > Archive>Volume 33, Issue 3, 2023 >110-115. DOI:10. 3969 / j.issn.1671-7856. 2023. 03. 014

Astrocytes play a major role in the pathogenesis of hepatic encephalopathy
DOI:
                        10. 3969 / j.issn.1671-7856. 2023. 03. 014
                    
CSTR:
                        [cstr]
                    
Author:
                        WU RuiWU Rui
1. Department of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site
DING JunDING Jun
1. Department of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site
CHENG ChiCHENG Chi
1. Department of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site
YU TianYU Tian
2. Guizhou Key Laboratory of Anesthesia and Organ Protection, Zunyi Medical University, Zunyi 563000
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site

                    
Affiliation:1. Department of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China. 2. Guizhou Key Laboratory of Anesthesia and Organ Protection, Zunyi Medical University, Zunyi 563000
Clc Number:R-33
Fund Project:

Article

Figures

Metrics

Reference

Cited by

Materials

Comments

Abstract:

Hepatic encephalopathy (HE) is a neuropsychiatric syndrome that frequently occurs in the course of acute or chronic liver diseases or an abnormal portal shunt. Astrocytes play a critical role in the pathogenesis of HE. In recent years, HE has been found to be accompanied by morphological and functional changes of astrocytes and HE is effectively alleviated by drugs that act on astrocytes. Therefore, astrocytes may be a potential therapeutic target for HE. This article reviews the role of astrocytes in HE to provide new clinical ideas for treatment.

Key words:hepatic encephalopathy; astrocyte; ammonia; glutamine; energy metabolism; senescence; autophagy

Get Citation

Copy

Article Metrics

Abstract:
PDF:
HTML:
Cited by:

History

Received:June 16,2022
Revised:
Adopted:
Online: April 13,2023
Published:

Home

About this journal

Editorial Board

Info for Author

Contact Us

中文版

Get Citation

Share

Article Metrics

History

Article QR Code