Types of rat flap models and strategies for flap survival
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1. Yuncheng Central Hospital, Yuncheng 044000, China. 2. Shanxi Medical University, Taiyuan 030607

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    Abstract:

    Flap surgery is a surgical method to cover a defect and remove a wound after skin and subcutaneous tissue, including deep muscles, are cut by surgery. It is widely used for various skin defects and bone exposure that cannot be repaired by traditional surgical skin grafting. However, finding vessels to supply the flap and protect the blood supply of the flap after transplantation is difficult. To better understand the blood supply of the flap and explore how to improve the survival rate of the flap, numerous researchers have established a large number of rat models of the flap and applied various treatment schemes to increase the survival rate of the transplanted flap in clinical practice. Currently, many rat models of skin flaps with various parts and functions have been established, and various treatment schemes have been developed. Through animal experiments, the operation mode of skin flap surgery has been improved and expanded, and the necrosis rate of a skin flap has been reduced. Moreover, some new treatment schemes have been developed, which lays a theoretical foundation for the development of skin flap surgery in the future. The purpose and significance of this paper was to summarize the types of existing rat flap models and their flap survival strategies, future technological innovations and to provide a corresponding basis for the follow-up study of rat skin flap model.

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History
  • Received:December 12,2022
  • Online: August 02,2023
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