Research progress in experimental models of pulmonary arterial hypertension

doi:10. 3969 / j.issn.1671-7856. 2023. 09. 010

Home > Archive>Volume 33, Issue 9, 2023 >79-89. DOI:10. 3969 / j.issn.1671-7856. 2023. 09. 010

Research progress in experimental models of pulmonary arterial hypertension
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                        10. 3969 / j.issn.1671-7856. 2023. 09. 010
                    
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Author:
                        XIE JinchengXIE Jincheng
1. the Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, China. 3. Scientific Research Platform, the Second Clinical Medical College, Guangdong Medical University, Dongguan 523808
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XIAO Mengyuan2,3,1XIAO Mengyuan
1. the Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, China.
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DENG ShaodongDENG Shaodong
2. the First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523710. 3. Scientific Research Platform, the Second Clinical Medical College, Guangdong Medical University, Dongguan 523808
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CHEN Jianying2,3,1CHEN Jianying
1. the Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, China.
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Affiliation:1. the Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, China. 2. the First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523710. 3. Scientific Research Platform, the Second Clinical Medical College, Guangdong Medical University, Dongguan 523808
Clc Number:R-33
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Abstract:

Pulmonary arterial hypertension is a chronic progressive disease that, if not treated promptly, can ultimately lead to right heart failure and even death. To explore the pathogenesis of pulmonary arterial hypertension and develop more effective treatments, it is necessary to establish an experimental model corresponding to its pathogenesis. In this review, PubMed, ScienceDirect, Wiley, and CNKI were used to search the relevant literature. The establishment method and research progress of experimental models of pulmonary arterial hypertension in recent years were systematically summarized. Moreover, the pathological characteristics involved in these experimental models were classified and discussed to provide a reference to study the pathogenesis of pulmonary arterial hypertension.

Key words:pulmonary arterial hypertension; animal model; cell model

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Received:March 01,2023
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Online: November 09,2023
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