Advances of CREB in the regulation of memory through synaptic plasticity and its relationship with Alzheimer’s disease

doi:10. 3969 / j.issn.1671-7856. 2023. 11. 014

Home > Archive>Volume 33, Issue 11, 2023 >104-109. DOI:10. 3969 / j.issn.1671-7856. 2023. 11. 014

Advances of CREB in the regulation of memory through synaptic plasticity and its relationship with Alzheimer’s disease
DOI:
                        10. 3969 / j.issn.1671-7856. 2023. 11. 014
                    
CSTR:
                        [cstr]
                    
Author:
                        LUO ZhuohuiLUO Zhuohui
1.Key Laboratory of Human Disease Comparative Medicine, National Health Commission of China (NHC), Institute of Laboratory Animal Science, Peking Union Medicine College, Chinese Academy of Medical Sciences, Beijing 100021, China
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site
PANG ShuoPANG Shuo
1.Key Laboratory of Human Disease Comparative Medicine, National Health Commission of China (NHC), Institute of Laboratory Animal Science, Peking Union Medicine College, Chinese Academy of Medical Sciences, Beijing 100021, China
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site
ZHANG LianfengZHANG Lianfeng
1.Key Laboratory of Human Disease Comparative Medicine, National Health Commission of China (NHC), Institute of Laboratory Animal Science, Peking Union Medicine College, Chinese Academy of Medical Sciences, Beijing 100021, China. 2. Neuroscience Center, Chinese Academy of Medical Sciences, Beijing 100730
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site

                    
Affiliation:1.Key Laboratory of Human Disease Comparative Medicine, National Health Commission of China (NHC), Institute of Laboratory Animal Science, Peking Union Medicine College, Chinese Academy of Medical Sciences, Beijing 100021, China. 2. Neuroscience Center, Chinese Academy of Medical Sciences, Beijing 100730
Clc Number:R-33
Fund Project:

Article

Figures

Metrics

Reference

Cited by

Materials

Comments

Abstract:

Alzheimer’s disease (AD) is an irreversible heterogeneous neurodegenerative disease. AD patients have memory loss and impaired synaptic plasticity. In view of cAMP responsive element-binding protein (CREB), which is intimately associated with synaptic plasticity, this article summarizes the research progress on the structure, signaling pathways, downstream genes, and relative memory regulation. The involvement of CREB in AD development serves as a reference for AD researchers to improve synaptic plasticity.

Key words:CREB; synaptic plasticity; long term memory; Alzheimer’s disease

Get Citation

Copy

Article Metrics

Abstract:533
PDF: 240
HTML: 0
Cited by: 0

History

Received:January 05,2023
Revised:
Adopted:
Online: December 29,2023
Published:

Home

About this journal

Editorial Board

Info for Author

Contact Us

中文版

Get Citation

Share

Article Metrics

History

Article QR Code