As the basic carrier and key condition for research in the fields of life science, medicine and pharmacy, laboratory animals have played an extremely important role in the development of modern science. Animal welfare ethics is built on the moral foundation of human civilization and is a product of social and economic development to a certain stage. From a scientific point of view, treating animals well is both a humanitarian need and a need for scientific experiments. This paper elaborates the role and significance of laboratory animal welfare from the aspects of the development of laboratory animal welfare ethics and the content of regulations and policies, whether and how to establish a memorial day and monument for laboratory animals, and calls on experimental personnel to follow the “3R” principle and enhance their sense of responsibility and awareness of norms.