Research progress in evaluation of type 2 diabetic peripheral neuropathy animal model
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1. School of Acupuncture-Moxibustion, Chengdu University of TCM, Chengdu 610075, China. 2. Graduate School, Chengdu University of TCM, Chengdu 610075. 3. Office of Asset and Laboratory Management, Chengdu University of TCM, Chengdu 611137

Clc Number:

R-33

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    Abstract:

    Diabetic peripheral neuropathy is a common diabetic complication. Presently, our understanding of its pathogenesis is incomplete, and there are no effective treatment options. In-depth research requires the use of animal experiments. The criteria for modeling success and the evaluation method for peripheral nerve function recovery are critical for carrying out animal experiments into type 2 diabetic peripheral neuropathy. However, but there has been a lack of systematic interrogation and analysis of the evaluation method used with type 2 diabetic peripheral neuropathy models. Therefore, the author reviewed the recent data, summarized and analyzed the evaluation method used for animal models of type 2 diabetic peripheral neuropathy of small and large nerve fibers, and proposed future directions for development, providing a reference for related research.

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History
  • Received:April 18,2023
  • Online: March 04,2024
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