Overview of in vitro skin models of transdermal drug delivery systems
CSTR:
Author:
Affiliation:

1. College of Pharmacy, Dali University, Dali 671000, China. 2. Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, Dali University, Dali 671000. 3. National Joint Engineering Research Center for the Development of Medicinal Special Insects, Dali University, Dali 671000. 4. College of Public Health, Dali University, Dali 671000

Clc Number:

R-33

  • Article
  • | |
  • Metrics
  • | | |
  • Cited by
  • | |
  • Comments
    Abstract:

    Skin modeling of transdermal drug delivery system refers to experimental models that mimic the structure and function of human skin to explore and evaluate absorption, penetration, and efficacy of medicines in transdermal drug delivery. It provides an alternative to traditional human skin experiments and reduces the use of human skin in medical research, which is convenient, controllable, and cost effective. For skin models of transdermal drug delivery systems, this article introduces commonly used animal skin models, artificial skin models, and recombinant human skin models from the perspective of the transdermal absorption pathway of medicines, and analyzes their advantages,disadvantages, and applications so provide references the research and development of transdermal formulations and topical therapies.

    Reference
    Related
    Cited by
Get Citation
Share
Article Metrics
  • Abstract:
  • PDF:
  • HTML:
  • Cited by:
History
  • Received:June 22,2023
  • Online: May 07,2024
Article QR Code