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Home > Archive>Volume 34, Issue 3, 2024 >149-160. DOI:10.3969/j.issn.1671-7856.2024.03.019
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Etiology, pathogenesis and animal model building of premature ovarian insufficiency
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College of Pharmacy, Harbin University of Commerce, Harbin 150076, China

Clc Number:

R-33

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    Abstract:

    Premature ovarian insufficiency (POI), also known as “ ovarian insufficiency”, has an incidence of 1% ~ 5%. The incidence has been on the rise in recent years, seriously affecting women’s physical and mental health and quality of life. At present, the cause and mechanisms of POI are still unclear, and the method and applications of model construction are also confusing. Most models have some shortcomings in pertinence and stability. The limitations greatly limit research into the clinical diagnosis and treatment of POI. This paper summarizes and discusses the etiology and pathogenesis of POI and the construction of POI animal models to provide a comprehensive reference for those studying POI.

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History
  • Received:July 12,2023
  • Online: May 29,2024
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