Parkinson’ s disease ( PD) is a common neurodegenerative disease characterized by progressive degeneration of nigrostriatal dopaminergic neurons and Lewy body morphology. The pathogenic mechanism of PD,however, is not yet fully understood, and the increase in the number of patients places a huge burden on society.Acupuncture, as a distinctive therapy in traditional Chinese medicine, has been widely used to improve motor and non-motor symptoms in patients with PD, possibly acting via a mechanism closely related to the regulation of programmed cell death ( PCD )-related signaling pathways. PCD, including apoptosis, necroptosis, cellular pyroptosis, ferroptosis, and other forms, plays a key role in the process of neuronal damage in PD. This review thus considers the role of PCD in PD. Combined with research progress in acupuncture interventions for PCD, it provides new ideas to clarify the scientific basis of acupuncture treatment for PD, and supports the development of new treatment strategies.