Design and implementation of a novel behavioral experiment stimulation device
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1. School of Basic Medical Sciences, College of Medicine, Shandong University, Jinan 250012, China.2. Academy of Medical Sciences, Zhengzhou University, Zhengzhou 450052.3. Chengdu Taimeng Software Company Limited, Chengdu 610101

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B841. 4

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    Abstract:

    Objective To address limitations of conventional behavioral experimental apparatuse and to design an intelligent, integrated, and precise novel stimulation device for psychology experiments to investigate the facilitative effects of adrenoceptor agonists on learned anxiety. Methods We developed an integrated behavioral experiment stimulation device combining electrical / acoustic stimulation, visual observation, thermostatic control, and computerized operation. The core components included a control system, main microprocessor, power supply, electrical stimulator, noise stimulator, thermostatic unit, and visual observation chamber. We used the device to deliver conditioned auditory stimuli paired with unconditioned foot-shock stimuli to induce anxiety in rats. Results The device eliminated the drawbacks of fragmented operations and achieved precise synchronization of electrical and noise stimuli, ensured strict correlation between conditioned and unconditioned stimuli, and enabled programmable preset stimulation sequences. The device accordingly reduced the risk of operational error, significantly improved experimental repeatability, and increased students’ scientific understanding of anxiety behaviors. The device also demonstrated applicability to pain research and other behavioral experiments. Conclusions As a multifunctional instrument, this novel device represents a valuable addition to the traditional medical curriculum, by addressing teaching-oriented demands through medicine-engineering integration, advancing course development, and enhancing talent cultivation.

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History
  • Received:July 18,2025
  • Revised:
  • Adopted:
  • Online: February 10,2026
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