Objective To understand the biological characteristics of congenital cataract rats. Methods Expanding populations by breeding with the original group, then to observe reproductive performance and offspring growth and development. Results There was no significant differenceboth in the birth rate and the weaning number between the normal controlled group and cataract and microphthalmos cataract groups (p>0.05). Compared with other two groups,the cataract group had heavier weight at the second week after birth.In comparison between males of different groups, the cataract group growed faster at first two weeks after birth and the difference in weight was more obvious at fourth week after bieth(p<0.01) .In comparison between sexes, there was significant differencesin in weight between male and famale in the cataract group and the control group at the fifth week after birth (p<0.01), while the microphthalmos cataract group had significant differences at the sixth week (p<0.01). Conclusion Cataract gene in rats did not affect their reproductive rate, while the growth rate of pups had a certain impact.